Anterior Temporal Lobectomy in Refractory Complex Partial Seizures
نویسندگان
چکیده
منابع مشابه
Early antiepileptic drug reduction following anterior temporal lobectomy for medically intractable complex partial epilepsy
PURPOSE To determine the safety, in our practice, of allowing patient preference to influence the timing of antiepileptic drug (AED) reduction, once they became seizure-free after anterior temporal lobectomy (ATL). METHODS Thirty patients underwent anterior temporal lobectomy for medically intractable complex partial epilepsy at Loma Linda University Medical Center between December 1st 1991 a...
متن کاملTreatment of refractory complex partial seizures: role of vigabatrin
Vigabatrin (VGB) is an antiepileptic drug that was designed to inhibit GABA-transaminase, and increase levels of gamma-amino-butyric acid (GABA), a major inhibitory neurotransmitter in the brain. VGB has demonstrated efficacy as an adjunctive antiepileptic drug for refractory complex partial seizures (CPS) and for infantile spasms (IS). This review focuses on its use for complex partial seizure...
متن کاملGamma knife radiosurgery for the treatment of recurrent seizures after incomplete anterior temporal lobectomy
To evaluate the efficacy and safety of gamma knife radiosurgery (GKS) in treating temporal lobe epilepsy, GKS was performed in four adult patients with recurrent complex partial seizures who underwent incomplete anterior temporal lobectomy (ATL) but were reluctant to undergo a second resective surgery. A marginal dose of 24.5-25Gy, corresponding to 65-70% isodose curve, was delivered to the tre...
متن کاملAdjunctive perampanel for refractory partial-onset seizures
Methods: This was a multicenter, double-blind, placebo-controlled trial (ClinicalTrials.gov identifier: NCT00699972). Patients ( 12 years, with ongoing seizures despite 1–3 AEDs) were randomized (1:1:1) to once-daily perampanel 8 mg, 12 mg, or placebo. Following baseline (6 weeks), patients entered a 19-week double-blind phase: 6-week titration (2 mg/week increments to target dose) followed by ...
متن کاملAnterior temporal lobectomy for older adults with mesial temporal sclerosis.
OBJECTIVE To compare postoperative seizure-free survival between older and younger adults. METHODS A retrospective cohort of 107 temporal lobe epilepsy patients with a diagnosis of mesial temporal sclerosis (MTS) received anterior temporal lobectomy (ATL) between 1993 and 2014. We divided the lower three quartiles (younger) and top quartile (older, all 47+ years) of patients, then reviewed pa...
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ژورنال
عنوان ژورنال: Pediatric Neurology Briefs
سال: 1990
ISSN: 2166-6482,1043-3155
DOI: 10.15844/pedneurbriefs-4-6-5